Research Use Only
PNC-27
· Reviewed by Aydan Myers, Lead Chemist · Evidence tier B
PNC-27 (PNC27) is a Research Use Only chemical-identity and literature reference on Costides, not for human or veterinary use. Published identity includes CAS 1159861-00-3, formula C188H293N53O44S, average MW 4032 Da, PubChem CID 16201774. It is indexed as p53-derived membrane-active peptide studied in cancer cell models.
Synonyms and vendor codes indexed here include PNC27, PNC-27. This page does not describe administration or dosing.
Key facts
| CAS Registry Number | 1159861-00-3 |
|---|---|
| Molecular formula | C188H293N53O44S |
| Average molecular weight | 4032 Da |
| PubChem CID | 16201774 |
| InChIKey | MZCACYLMMMXSKC-KOCFKOPYSA-N |
| Page type | Research identity monograph |
| Intended use | Research Use Only (reference) |
| Synonyms | PNC27, PNC-27 |
| Research notes | p53-derived membrane-active peptide studied in cancer cell models |
| Evidence tier | B |
| Last verified | 2026-08-21 |
Is PNC-27 for human use?
No. PNC-27 (PNC27) pages on Costides are Research Use Only reference materials. They are not medical advice and do not describe administration or dosing.
What is the CAS number of PNC-27?
The CAS number of PNC-27 (PNC27) is 1159861-00-3. Formula and molecular weight appear in the identity table when retrieved.
What is the molecular weight of PNC-27?
The average molecular weight of PNC-27 (PNC27) listed on Costides is 4032 Da.
Chemical identity table
| CAS Registry Number | 1159861-00-3 |
|---|---|
| Molecular formula | C188H293N53O44S |
| Average molecular weight | 4032 Da |
| PubChem CID | 16201774 |
| InChIKey | MZCACYLMMMXSKC-KOCFKOPYSA-N |
| Synonyms | PNC27, PNC-27 |
Frequently asked questions
- What is PNC-27?
- PNC-27 (PNC27) is a Research Use Only chemical-identity and literature reference on Costides, not for human or veterinary use. Published identity includes CAS 1159861-00-3, formula C188H293N53O44S, average MW 4032 Da, PubChem CID 16201774. It is indexed as p53-derived membrane-active peptide studied in cancer cell models. The CAS number of PNC-27 is 1159861-00-3. Research Use Only. Not for human or veterinary use.
- What is the CAS number of PNC-27?
- The CAS number of PNC-27 (PNC27) is 1159861-00-3. Formula and molecular weight appear in the identity table when retrieved.
- Is PNC-27 for human use?
- No. PNC-27 (PNC27) pages on Costides are Research Use Only reference materials. They are not medical advice and do not describe administration or dosing.
- What is the molecular weight of PNC-27?
- The average molecular weight of PNC-27 (PNC27) listed on Costides is 4032 Da.
- Can I buy PNC-27 from Costides?
- Yes. PNC-27 may appear in the Costides catalog as a Research Use Only 10-pack when published. Check the product listing for SKU, price, and CoA lots.
- Where does identity data for PNC-27 come from?
- Costides indexes registry and bibliographic sources (PubChem, CAS Common Chemistry, PubMed permalinks) when available. Outcome or efficacy claims are not restated on this page.
Citations
- PubChem CID 16201774
- CAS Common Chemistry 1159861-00-3
- HDM-2-Targeting Peptide PNC-27 Kills Cervical Cancer Cells but not Normal Cervical Cells. PMID 40750238
- Poptosis or Peptide-Induced Transmembrane Pore Formation: A Novel Way to Kill Cancer Cells without Affecting Normal Cells. PMID 38927351
- DOI for PMID 38927351 PMID 38927351
- Anti-Cancer Peptide PNC-27 Kills Cancer Cells by Unique Interactions with Plasma Membrane-Bound hdm-2 and with Mitochondrial Membranes Causing Mitochondrial Disruption. PMID 38802154
- Ketone Bodies Induce Unique Inhibition of Tumor Cell Proliferation and Enhance the Efficacy of Anti-Cancer Agents. PMID 37760956
- DOI for PMID 37760956 PMID 37760956