Research Use Only
FOXO4-DRI
· Reviewed by Aydan Myers, Lead Chemist · Evidence tier B
FOXO4-DRI (FOXO4) is a Research Use Only chemical-identity and literature reference on Costides, not for human or veterinary use. Published identity includes CAS 2460055-10-9, formula C228H388N86O64, average MW 5358 Da, PubChem CID 167312269. It is indexed as D-retro-inverso peptide designed to interfere with FOXO4–p53 interaction in senescence research.
Synonyms and vendor codes indexed here include FOXO4, FOXO4-DRI, FOXO4 D-Retro-Inverso. This page does not describe administration or dosing.
Key facts
| CAS Registry Number | 2460055-10-9 |
|---|---|
| Molecular formula | C228H388N86O64 |
| Average molecular weight | 5358 Da |
| PubChem CID | 167312269 |
| InChIKey | WVZCDZFJLXBWHG-XXZPGMBKSA-N |
| Page type | Research identity monograph |
| Intended use | Research Use Only (reference) |
| Synonyms | FOXO4, FOXO4-DRI, FOXO4 D-Retro-Inverso |
| Research notes | D-retro-inverso peptide designed to interfere with FOXO4–p53 interaction in senescence research |
| Evidence tier | B |
| Last verified | 2026-08-21 |
Is FOXO4-DRI for human use?
No. FOXO4-DRI (FOXO4) pages on Costides are Research Use Only reference materials. They are not medical advice and do not describe administration or dosing.
What is the CAS number of FOXO4-DRI?
The CAS number of FOXO4-DRI (FOXO4) is 2460055-10-9. Formula and molecular weight appear in the identity table when retrieved.
What is the molecular weight of FOXO4-DRI?
The average molecular weight of FOXO4-DRI (FOXO4) listed on Costides is 5358 Da.
Chemical identity table
| CAS Registry Number | 2460055-10-9 |
|---|---|
| Molecular formula | C228H388N86O64 |
| Average molecular weight | 5358 Da |
| PubChem CID | 167312269 |
| InChIKey | WVZCDZFJLXBWHG-XXZPGMBKSA-N |
| Synonyms | FOXO4, FOXO4-DRI, FOXO4 D-Retro-Inverso |
Frequently asked questions
- What is FOXO4-DRI?
- FOXO4-DRI (FOXO4) is a Research Use Only chemical-identity and literature reference on Costides, not for human or veterinary use. Published identity includes CAS 2460055-10-9, formula C228H388N86O64, average MW 5358 Da, PubChem CID 167312269. It is indexed as D-retro-inverso peptide designed to interfere with FOXO4–p53 interaction in senescence research. The CAS number of FOXO4-DRI is 2460055-10-9. Research Use Only. Not for human or veterinary use.
- What is the CAS number of FOXO4-DRI?
- The CAS number of FOXO4-DRI (FOXO4) is 2460055-10-9. Formula and molecular weight appear in the identity table when retrieved.
- Is FOXO4-DRI for human use?
- No. FOXO4-DRI (FOXO4) pages on Costides are Research Use Only reference materials. They are not medical advice and do not describe administration or dosing.
- What is the molecular weight of FOXO4-DRI?
- The average molecular weight of FOXO4-DRI (FOXO4) listed on Costides is 5358 Da.
- Can I buy FOXO4-DRI from Costides?
- Yes. FOXO4-DRI may appear in the Costides catalog as a Research Use Only 10-pack when published. Check the product listing for SKU, price, and CoA lots.
- Where does identity data for FOXO4-DRI come from?
- Costides indexes registry and bibliographic sources (PubChem, CAS Common Chemistry, PubMed permalinks) when available. Outcome or efficacy claims are not restated on this page.
Citations
- PubChem CID 167312269
- CAS Common Chemistry 2460055-10-9
- FOXO4 as a Redox-Sensitive Regulator of Antioxidant Defense and Cellular Senescence: Cysteine-Based Signaling, p53 Interaction, and Therapeutic Targeting. PMID 42510573
- DOI for PMID 42510573 PMID 42510573
- Acylglycerol Kinase Sensitizes Glioblastoma to Temozolomide via Limiting Mitochondrial Damage Related Cellular Senescence. PMID 42391447
- DOI for PMID 42391447 PMID 42391447
- Targeting the FOXO4-p53 axis by retro-inverso peptide senolytic agents: a pharmacological strategy to mitigate brain aging and cognitive decline. PMID 42024235
- DOI for PMID 42024235 PMID 42024235