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For laboratory research use only. Not for human or veterinary use.

Research Use Only

MOTS-c

· Reviewed by Aydan Myers, Lead Chemist · Evidence tier B

MOTS-c (MOTS) is a Research Use Only chemical-identity and literature reference on Costides, not for human or veterinary use. Published identity includes CAS 1627580-64-6, formula C101H152N28O22S2, average MW 2174.6 Da, PubChem CID 146675088. It is indexed as mitochondria-encoded peptide studied in metabolic stress models.

Synonyms and vendor codes indexed here include MOTS, MTSC, MTS-C, Mitochondrial open reading frame of the twelve S rRNA type-c. This page does not describe administration or dosing.

Research Use Only. Not for human or veterinary use. This page indexes chemical identity and citations. It is not medical advice and does not describe administration or dosing.

Key facts

MOTS-c key facts
CAS Registry Number1627580-64-6
Molecular formulaC101H152N28O22S2
Average molecular weight2174.6 Da
PubChem CID146675088
InChIKeyWYTHCOXVWRKRAH-LOKRTKBUSA-N
Page typeResearch identity monograph
Intended useResearch Use Only (reference)
SynonymsMOTS, MTSC, MTS-C, Mitochondrial open reading frame of the twelve S rRNA type-c
Research notesmitochondria-encoded peptide studied in metabolic stress models
Evidence tierB
Last verified2026-08-21

Is MOTS-c for human use?

No. MOTS-c (MOTS) pages on Costides are Research Use Only reference materials. They are not medical advice and do not describe administration or dosing.

What is the CAS number of MOTS-c?

The CAS number of MOTS-c (MOTS) is 1627580-64-6. Formula and molecular weight appear in the identity table when retrieved.

What is the molecular weight of MOTS-c?

The average molecular weight of MOTS-c (MOTS) listed on Costides is 2174.6 Da.

Chemical identity table

CAS Registry Number1627580-64-6
Molecular formulaC101H152N28O22S2
Average molecular weight2174.6 Da
PubChem CID146675088
InChIKeyWYTHCOXVWRKRAH-LOKRTKBUSA-N
SynonymsMOTS, MTSC, MTS-C, Mitochondrial open reading frame of the twelve S rRNA type-c

Catalog 10-packs

Frequently asked questions

What is MOTS-c?
MOTS-c (MOTS) is a Research Use Only chemical-identity and literature reference on Costides, not for human or veterinary use. Published identity includes CAS 1627580-64-6, formula C101H152N28O22S2, average MW 2174.6 Da, PubChem CID 146675088. It is indexed as mitochondria-encoded peptide studied in metabolic stress models. The CAS number of MOTS-c is 1627580-64-6. Research Use Only. Not for human or veterinary use.
What is the CAS number of MOTS-c?
The CAS number of MOTS-c (MOTS) is 1627580-64-6. Formula and molecular weight appear in the identity table when retrieved.
Is MOTS-c for human use?
No. MOTS-c (MOTS) pages on Costides are Research Use Only reference materials. They are not medical advice and do not describe administration or dosing.
What is the molecular weight of MOTS-c?
The average molecular weight of MOTS-c (MOTS) listed on Costides is 2174.6 Da.
Can I buy MOTS-c from Costides?
Yes. MOTS-c may appear in the Costides catalog as a Research Use Only 10-pack when published. Check the product listing for SKU, price, and CoA lots.
Where does identity data for MOTS-c come from?
Costides indexes registry and bibliographic sources (PubChem, CAS Common Chemistry, PubMed permalinks) when available. Outcome or efficacy claims are not restated on this page.

Citations

  1. PubChem CID 146675088
  2. CAS Common Chemistry 1627580-64-6
  3. Circulating mitochondrial-derived microproteins at rest and in response to an acute bout of endurance exercise in individuals with cerebral palsy. PMID 42349896
  4. DOI for PMID 42349896 PMID 42349896
  5. Mitochondrial-derived peptide MOTS-c activates metabolic signaling but blunts reparative function in human mesenchymal stromal cells. PMID 42324588
  6. DOI for PMID 42324588 PMID 42324588
  7. Mitochondrial peptide MOTS-c suppresses systemic and cardiac inflammasome activation in a diabetic rat model. PMID 42321010
  8. DOI for PMID 42321010 PMID 42321010