{"kind":"compound","id":"pnc-27","name":"PNC-27","url":"https://costides.us/us/research/pnc-27","last_verified":"2026-08-21","identity":{"cas":"1159861-00-3","formula":"C188H293N53O44S","mw":4032,"sequence":null,"sequence_3letter":null,"residues":null,"pubchem":16201774,"identity_note":null,"parent_ligand":null},"chunks":[{"id":"lead-pnc-27","type":"definition","heading":"What is PNC-27?","text":"PNC-27 (PNC27) is a Research Use Only chemical-identity and literature reference on Costides, not for human or veterinary use. Published identity includes CAS 1159861-00-3, formula C188H293N53O44S, average MW 4032 Da, PubChem CID 16201774. It is indexed as p53-derived membrane-active peptide studied in cancer cell models.","words":45},{"id":"def-pnc-27","type":"definition","heading":"PNC-27 overview","text":"PNC-27 (PNC27) is a Research Use Only chemical-identity and literature reference on Costides, not for human or veterinary use. Published identity includes CAS 1159861-00-3, formula C188H293N53O44S, average MW 4032 Da, PubChem CID 16201774. It is indexed as p53-derived membrane-active peptide studied in cancer cell models. Synonyms and vendor codes indexed here include PNC27, PNC-27. This page does not describe administration or dosing.","words":62},{"id":"id-pnc-27","type":"identity","heading":"PNC-27 chemical identity","text":"PNC-27 chemical identity: CAS 1159861-00-3; formula C188H293N53O44S; average MW 4032 Da; PubChem CID 16201774. Values come from the Costides peptide research index.","words":22},{"id":"policy-pnc-27","type":"policy","heading":"Research Use Only","text":"Research Use Only. Not for human or veterinary use. This page indexes chemical identity and citations. It is not medical advice and does not describe administration or dosing.","words":28},{"id":"pass-what-pnc-27","type":"definition","heading":"What is PNC-27?","text":"PNC-27 (PNC27) is a Research Use Only chemical-identity and literature reference on Costides, not for human or veterinary use. Published identity includes CAS 1159861-00-3, formula C188H293N53O44S, average MW 4032 Da, PubChem CID 16201774. It is indexed as p53-derived membrane-active peptide studied in cancer cell models.","words":45},{"id":"pass-human-pnc-27","type":"definition","heading":"Is PNC-27 for human use?","text":"No. PNC-27 (PNC27) pages on Costides are Research Use Only reference materials. They are not medical advice and do not describe administration or dosing.","words":24},{"id":"pass-cas-pnc-27","type":"definition","heading":"What is the CAS number of PNC-27?","text":"The CAS number of PNC-27 (PNC27) is 1159861-00-3. Formula and molecular weight appear in the identity table when retrieved.","words":19},{"id":"pass-mw-pnc-27","type":"definition","heading":"What is the molecular weight of PNC-27?","text":"The average molecular weight of PNC-27 (PNC27) listed on Costides is 4032 Da.","words":13},{"id":"faq-pnc-27-1","type":"faq","heading":"What is PNC-27?","text":"PNC-27 (PNC27) is a Research Use Only chemical-identity and literature reference on Costides, not for human or veterinary use. Published identity includes CAS 1159861-00-3, formula C188H293N53O44S, average MW 4032 Da, PubChem CID 16201774. It is indexed as p53-derived membrane-active peptide studied in cancer cell models. The CAS number of PNC-27 is 1159861-00-3. Research Use Only. Not for human or veterinary use.","words":61},{"id":"faq-pnc-27-2","type":"faq","heading":"What is the CAS number of PNC-27?","text":"The CAS number of PNC-27 (PNC27) is 1159861-00-3. Formula and molecular weight appear in the identity table when retrieved.","words":19},{"id":"faq-pnc-27-3","type":"faq","heading":"Is PNC-27 for human use?","text":"No. PNC-27 (PNC27) pages on Costides are Research Use Only reference materials. They are not medical advice and do not describe administration or dosing.","words":24},{"id":"faq-pnc-27-4","type":"faq","heading":"What is the molecular weight of PNC-27?","text":"The average molecular weight of PNC-27 (PNC27) listed on Costides is 4032 Da.","words":13},{"id":"faq-pnc-27-5","type":"faq","heading":"Can I buy PNC-27 from Costides?","text":"Yes. PNC-27 may appear in the Costides catalog as a Research Use Only 10-pack when published. Check the product listing for SKU, price, and CoA lots.","words":26},{"id":"faq-pnc-27-6","type":"faq","heading":"Where does identity data for PNC-27 come from?","text":"Costides indexes registry and bibliographic sources (PubChem, CAS Common Chemistry, PubMed permalinks) when available. Outcome or efficacy claims are not restated on this page.","words":24},{"id":"cite-pnc-27-1","type":"citation","heading":"PubChem CID 16201774","text":"PubChem CID 16201774. https://pubchem.ncbi.nlm.nih.gov/compound/16201774","words":4},{"id":"cite-pnc-27-2","type":"citation","heading":"CAS Common Chemistry 1159861-00-3","text":"CAS Common Chemistry 1159861-00-3. https://commonchemistry.cas.org/detail?cas_rn=1159861-00-3","words":5},{"id":"cite-pnc-27-3","type":"citation","heading":"HDM-2-Targeting Peptide PNC-27 Kills Cervical Cancer Cells but not Normal Cervical Cells.","text":"HDM-2-Targeting Peptide PNC-27 Kills Cervical Cancer Cells but not Normal Cervical Cells.. PMID 40750238. https://pubmed.ncbi.nlm.nih.gov/40750238/","words":15},{"id":"cite-pnc-27-4","type":"citation","heading":"Poptosis or Peptide-Induced Transmembrane Pore Formation: A Novel Way to Kill Cancer Cells without Affecting Normal Cells.","text":"Poptosis or Peptide-Induced Transmembrane Pore Formation: A Novel Way to Kill Cancer Cells without Affecting Normal Cells.. PMID 38927351. https://pubmed.ncbi.nlm.nih.gov/38927351/","words":20},{"id":"cite-pnc-27-5","type":"citation","heading":"DOI for PMID 38927351","text":"DOI for PMID 38927351. PMID 38927351. https://doi.org/10.3390/biomedicines12061144","words":7},{"id":"cite-pnc-27-6","type":"citation","heading":"Anti-Cancer Peptide PNC-27 Kills Cancer Cells by Unique Interactions with Plasma Membrane-Bound hdm-2 and with Mitochondrial Membranes Causing Mitochondrial Disruption.","text":"Anti-Cancer Peptide PNC-27 Kills Cancer Cells by Unique Interactions with Plasma Membrane-Bound hdm-2 and with Mitochondrial Membranes Causing Mitochondrial Disruption.. PMID 38802154. https://pubmed.ncbi.nlm.nih.gov/38802154/","words":23}],"faqs":[{"question":"What is PNC-27?","answer":"PNC-27 (PNC27) is a Research Use Only chemical-identity and literature reference on Costides, not for human or veterinary use. Published identity includes CAS 1159861-00-3, formula C188H293N53O44S, average MW 4032 Da, PubChem CID 16201774. It is indexed as p53-derived membrane-active peptide studied in cancer cell models. The CAS number of PNC-27 is 1159861-00-3. Research Use Only. Not for human or veterinary use."},{"question":"What is the CAS number of PNC-27?","answer":"The CAS number of PNC-27 (PNC27) is 1159861-00-3. Formula and molecular weight appear in the identity table when retrieved."},{"question":"Is PNC-27 for human use?","answer":"No. PNC-27 (PNC27) pages on Costides are Research Use Only reference materials. They are not medical advice and do not describe administration or dosing."},{"question":"What is the molecular weight of PNC-27?","answer":"The average molecular weight of PNC-27 (PNC27) listed on Costides is 4032 Da."},{"question":"Can I buy PNC-27 from Costides?","answer":"Yes. PNC-27 may appear in the Costides catalog as a Research Use Only 10-pack when published. Check the product listing for SKU, price, and CoA lots."},{"question":"Where does identity data for PNC-27 come from?","answer":"Costides indexes registry and bibliographic sources (PubChem, CAS Common Chemistry, PubMed permalinks) when available. Outcome or efficacy claims are not restated on this page."}],"links":[{"rel":"canonical","href":"https://costides.us/us/research/pnc-27"},{"rel":"rag","href":"https://costides.us/api/rag/compound/pnc-27"},{"rel":"cas","href":"https://costides.us/us/cas/1159861-00-3"},{"rel":"llms","href":"https://costides.us/llms.txt"}]}