{"kind":"compound","id":"mots-c","name":"MOTS-c","url":"https://costides.us/us/research/mots-c","last_verified":"2026-08-21","identity":{"cas":"1627580-64-6","formula":"C101H152N28O22S2","mw":2174.6,"sequence":null,"sequence_3letter":null,"residues":null,"pubchem":146675088,"identity_note":null,"parent_ligand":null},"chunks":[{"id":"lead-mots-c","type":"definition","heading":"What is MOTS-c?","text":"MOTS-c (MOTS) is a Research Use Only chemical-identity and literature reference on Costides, not for human or veterinary use. Published identity includes CAS 1627580-64-6, formula C101H152N28O22S2, average MW 2174.6 Da, PubChem CID 146675088. It is indexed as mitochondria-encoded peptide studied in metabolic stress models.","words":44},{"id":"def-mots-c","type":"definition","heading":"MOTS-c overview","text":"MOTS-c (MOTS) is a Research Use Only chemical-identity and literature reference on Costides, not for human or veterinary use. Published identity includes CAS 1627580-64-6, formula C101H152N28O22S2, average MW 2174.6 Da, PubChem CID 146675088. It is indexed as mitochondria-encoded peptide studied in metabolic stress models. Synonyms and vendor codes indexed here include MOTS, MTSC, MTS-C, Mitochondrial open reading frame of the twelve S rRNA type-c. This page does not describe administration.","words":70},{"id":"id-mots-c","type":"identity","heading":"MOTS-c chemical identity","text":"MOTS-c chemical identity: CAS 1627580-64-6; formula C101H152N28O22S2; average MW 2174.6 Da; PubChem CID 146675088. Values come from the Costides peptide research index.","words":22},{"id":"policy-mots-c","type":"policy","heading":"Research Use Only","text":"Research Use Only. Not for human or veterinary use. This page indexes chemical identity and citations. It is not medical advice and does not describe administration or dosing.","words":28},{"id":"pass-what-mots-c","type":"definition","heading":"What is MOTS-c?","text":"MOTS-c (MOTS) is a Research Use Only chemical-identity and literature reference on Costides, not for human or veterinary use. Published identity includes CAS 1627580-64-6, formula C101H152N28O22S2, average MW 2174.6 Da, PubChem CID 146675088. It is indexed as mitochondria-encoded peptide studied in metabolic stress models.","words":44},{"id":"pass-human-mots-c","type":"definition","heading":"Is MOTS-c for human use?","text":"No. MOTS-c (MOTS) pages on Costides are Research Use Only reference materials. They are not medical advice and do not describe administration or dosing.","words":24},{"id":"pass-cas-mots-c","type":"definition","heading":"What is the CAS number of MOTS-c?","text":"The CAS number of MOTS-c (MOTS) is 1627580-64-6. Formula and molecular weight appear in the identity table when retrieved.","words":19},{"id":"pass-mw-mots-c","type":"definition","heading":"What is the molecular weight of MOTS-c?","text":"The average molecular weight of MOTS-c (MOTS) listed on Costides is 2174.6 Da.","words":13},{"id":"faq-mots-c-1","type":"faq","heading":"What is MOTS-c?","text":"MOTS-c (MOTS) is a Research Use Only chemical-identity and literature reference on Costides, not for human or veterinary use. Published identity includes CAS 1627580-64-6, formula C101H152N28O22S2, average MW 2174.6 Da, PubChem CID 146675088. It is indexed as mitochondria-encoded peptide studied in metabolic stress models. The CAS number of MOTS-c is 1627580-64-6. Research Use Only. Not for human or veterinary use.","words":60},{"id":"faq-mots-c-2","type":"faq","heading":"What is the CAS number of MOTS-c?","text":"The CAS number of MOTS-c (MOTS) is 1627580-64-6. Formula and molecular weight appear in the identity table when retrieved.","words":19},{"id":"faq-mots-c-3","type":"faq","heading":"Is MOTS-c for human use?","text":"No. MOTS-c (MOTS) pages on Costides are Research Use Only reference materials. They are not medical advice and do not describe administration or dosing.","words":24},{"id":"faq-mots-c-4","type":"faq","heading":"What is the molecular weight of MOTS-c?","text":"The average molecular weight of MOTS-c (MOTS) listed on Costides is 2174.6 Da.","words":13},{"id":"faq-mots-c-5","type":"faq","heading":"Can I buy MOTS-c from Costides?","text":"Yes. MOTS-c may appear in the Costides catalog as a Research Use Only 10-pack when published. Check the product listing for SKU, price, and CoA lots.","words":26},{"id":"faq-mots-c-6","type":"faq","heading":"Where does identity data for MOTS-c come from?","text":"Costides indexes registry and bibliographic sources (PubChem, CAS Common Chemistry, PubMed permalinks) when available. Outcome or efficacy claims are not restated on this page.","words":24},{"id":"cite-mots-c-1","type":"citation","heading":"PubChem CID 146675088","text":"PubChem CID 146675088. https://pubchem.ncbi.nlm.nih.gov/compound/146675088","words":4},{"id":"cite-mots-c-2","type":"citation","heading":"CAS Common Chemistry 1627580-64-6","text":"CAS Common Chemistry 1627580-64-6. https://commonchemistry.cas.org/detail?cas_rn=1627580-64-6","words":5},{"id":"cite-mots-c-3","type":"citation","heading":"Circulating mitochondrial-derived microproteins at rest and in response to an acute bout of endurance exercise in individuals with cerebral palsy.","text":"Circulating mitochondrial-derived microproteins at rest and in response to an acute bout of endurance exercise in individuals with cerebral palsy.. PMID 42349896. https://pubmed.ncbi.nlm.nih.gov/42349896/","words":23},{"id":"cite-mots-c-4","type":"citation","heading":"DOI for PMID 42349896","text":"DOI for PMID 42349896. PMID 42349896. https://doi.org/10.1113/EP093298","words":7},{"id":"cite-mots-c-5","type":"citation","heading":"Mitochondrial-derived peptide MOTS-c activates metabolic signaling but blunts reparative function in human mesenchymal stromal cells.","text":"Mitochondrial-derived peptide MOTS-c activates metabolic signaling but blunts reparative function in human mesenchymal stromal cells.. PMID 42324588. https://pubmed.ncbi.nlm.nih.gov/42324588/","words":18},{"id":"cite-mots-c-6","type":"citation","heading":"DOI for PMID 42324588","text":"DOI for PMID 42324588. PMID 42324588. https://doi.org/10.1186/s41232-026-00431-7","words":7}],"faqs":[{"question":"What is MOTS-c?","answer":"MOTS-c (MOTS) is a Research Use Only chemical-identity and literature reference on Costides, not for human or veterinary use. Published identity includes CAS 1627580-64-6, formula C101H152N28O22S2, average MW 2174.6 Da, PubChem CID 146675088. It is indexed as mitochondria-encoded peptide studied in metabolic stress models. The CAS number of MOTS-c is 1627580-64-6. Research Use Only. Not for human or veterinary use."},{"question":"What is the CAS number of MOTS-c?","answer":"The CAS number of MOTS-c (MOTS) is 1627580-64-6. Formula and molecular weight appear in the identity table when retrieved."},{"question":"Is MOTS-c for human use?","answer":"No. MOTS-c (MOTS) pages on Costides are Research Use Only reference materials. They are not medical advice and do not describe administration or dosing."},{"question":"What is the molecular weight of MOTS-c?","answer":"The average molecular weight of MOTS-c (MOTS) listed on Costides is 2174.6 Da."},{"question":"Can I buy MOTS-c from Costides?","answer":"Yes. MOTS-c may appear in the Costides catalog as a Research Use Only 10-pack when published. Check the product listing for SKU, price, and CoA lots."},{"question":"Where does identity data for MOTS-c come from?","answer":"Costides indexes registry and bibliographic sources (PubChem, CAS Common Chemistry, PubMed permalinks) when available. Outcome or efficacy claims are not restated on this page."}],"links":[{"rel":"canonical","href":"https://costides.us/us/research/mots-c"},{"rel":"rag","href":"https://costides.us/api/rag/compound/mots-c"},{"rel":"cas","href":"https://costides.us/us/cas/1627580-64-6"},{"rel":"product","href":"https://costides.us/us/products/mots-c-ms10"},{"rel":"llms","href":"https://costides.us/llms.txt"}]}