{"kind":"compound","id":"foxo4-dri","name":"FOXO4-DRI","url":"https://costides.us/us/research/foxo4-dri","last_verified":"2026-08-21","identity":{"cas":"2460055-10-9","formula":"C228H388N86O64","mw":5358,"sequence":null,"sequence_3letter":null,"residues":null,"pubchem":167312269,"identity_note":null,"parent_ligand":null},"chunks":[{"id":"lead-foxo4-dri","type":"definition","heading":"What is FOXO4-DRI?","text":"FOXO4-DRI (FOXO4) is a Research Use Only chemical-identity and literature reference on Costides, not for human or veterinary use. Published identity includes CAS 2460055-10-9, formula C228H388N86O64, average MW 5358 Da, PubChem CID 167312269. It is indexed as D-retro-inverso peptide designed to interfere with FOXO4–p53 interaction in senescence research.","words":48},{"id":"def-foxo4-dri","type":"definition","heading":"FOXO4-DRI overview","text":"FOXO4-DRI (FOXO4) is a Research Use Only chemical-identity and literature reference on Costides, not for human or veterinary use. Published identity includes CAS 2460055-10-9, formula C228H388N86O64, average MW 5358 Da, PubChem CID 167312269. It is indexed as D-retro-inverso peptide designed to interfere with FOXO4–p53 interaction in senescence research. Synonyms and vendor codes indexed here include FOXO4, FOXO4-DRI, FOXO4 D-Retro-Inverso. This page does not describe administration or dosing.","words":67},{"id":"id-foxo4-dri","type":"identity","heading":"FOXO4-DRI chemical identity","text":"FOXO4-DRI chemical identity: CAS 2460055-10-9; formula C228H388N86O64; average MW 5358 Da; PubChem CID 167312269. Values come from the Costides peptide research index.","words":22},{"id":"policy-foxo4-dri","type":"policy","heading":"Research Use Only","text":"Research Use Only. Not for human or veterinary use. This page indexes chemical identity and citations. It is not medical advice and does not describe administration or dosing.","words":28},{"id":"pass-what-foxo4-dri","type":"definition","heading":"What is FOXO4-DRI?","text":"FOXO4-DRI (FOXO4) is a Research Use Only chemical-identity and literature reference on Costides, not for human or veterinary use. Published identity includes CAS 2460055-10-9, formula C228H388N86O64, average MW 5358 Da, PubChem CID 167312269. It is indexed as D-retro-inverso peptide designed to interfere with FOXO4–p53 interaction in senescence research.","words":48},{"id":"pass-human-foxo4-dri","type":"definition","heading":"Is FOXO4-DRI for human use?","text":"No. FOXO4-DRI (FOXO4) pages on Costides are Research Use Only reference materials. They are not medical advice and do not describe administration or dosing.","words":24},{"id":"pass-cas-foxo4-dri","type":"definition","heading":"What is the CAS number of FOXO4-DRI?","text":"The CAS number of FOXO4-DRI (FOXO4) is 2460055-10-9. Formula and molecular weight appear in the identity table when retrieved.","words":19},{"id":"pass-mw-foxo4-dri","type":"definition","heading":"What is the molecular weight of FOXO4-DRI?","text":"The average molecular weight of FOXO4-DRI (FOXO4) listed on Costides is 5358 Da.","words":13},{"id":"faq-foxo4-dri-1","type":"faq","heading":"What is FOXO4-DRI?","text":"FOXO4-DRI (FOXO4) is a Research Use Only chemical-identity and literature reference on Costides, not for human or veterinary use. Published identity includes CAS 2460055-10-9, formula C228H388N86O64, average MW 5358 Da, PubChem CID 167312269. It is indexed as D-retro-inverso peptide designed to interfere with FOXO4–p53 interaction in senescence research. The CAS number of FOXO4-DRI is 2460055-10-9. Research Use Only. Not for human or veterinary use.","words":64},{"id":"faq-foxo4-dri-2","type":"faq","heading":"What is the CAS number of FOXO4-DRI?","text":"The CAS number of FOXO4-DRI (FOXO4) is 2460055-10-9. Formula and molecular weight appear in the identity table when retrieved.","words":19},{"id":"faq-foxo4-dri-3","type":"faq","heading":"Is FOXO4-DRI for human use?","text":"No. FOXO4-DRI (FOXO4) pages on Costides are Research Use Only reference materials. They are not medical advice and do not describe administration or dosing.","words":24},{"id":"faq-foxo4-dri-4","type":"faq","heading":"What is the molecular weight of FOXO4-DRI?","text":"The average molecular weight of FOXO4-DRI (FOXO4) listed on Costides is 5358 Da.","words":13},{"id":"faq-foxo4-dri-5","type":"faq","heading":"Can I buy FOXO4-DRI from Costides?","text":"Yes. FOXO4-DRI may appear in the Costides catalog as a Research Use Only 10-pack when published. Check the product listing for SKU, price, and CoA lots.","words":26},{"id":"faq-foxo4-dri-6","type":"faq","heading":"Where does identity data for FOXO4-DRI come from?","text":"Costides indexes registry and bibliographic sources (PubChem, CAS Common Chemistry, PubMed permalinks) when available. Outcome or efficacy claims are not restated on this page.","words":24},{"id":"cite-foxo4-dri-1","type":"citation","heading":"PubChem CID 167312269","text":"PubChem CID 167312269. https://pubchem.ncbi.nlm.nih.gov/compound/167312269","words":4},{"id":"cite-foxo4-dri-2","type":"citation","heading":"CAS Common Chemistry 2460055-10-9","text":"CAS Common Chemistry 2460055-10-9. https://commonchemistry.cas.org/detail?cas_rn=2460055-10-9","words":5},{"id":"cite-foxo4-dri-3","type":"citation","heading":"FOXO4 as a Redox-Sensitive Regulator of Antioxidant Defense and Cellular Senescence: Cysteine-Based Signaling, p53 Interaction, and Therapeutic Targeting.","text":"FOXO4 as a Redox-Sensitive Regulator of Antioxidant Defense and Cellular Senescence: Cysteine-Based Signaling, p53 Interaction, and Therapeutic Targeting.. PMID 42510573. https://pubmed.ncbi.nlm.nih.gov/42510573/","words":21},{"id":"cite-foxo4-dri-4","type":"citation","heading":"DOI for PMID 42510573","text":"DOI for PMID 42510573. PMID 42510573. https://doi.org/10.3390/antiox15070842","words":7},{"id":"cite-foxo4-dri-5","type":"citation","heading":"Acylglycerol Kinase Sensitizes Glioblastoma to Temozolomide via Limiting Mitochondrial Damage Related Cellular Senescence.","text":"Acylglycerol Kinase Sensitizes Glioblastoma to Temozolomide via Limiting Mitochondrial Damage Related Cellular Senescence.. PMID 42391447. https://pubmed.ncbi.nlm.nih.gov/42391447/","words":16},{"id":"cite-foxo4-dri-6","type":"citation","heading":"DOI for PMID 42391447","text":"DOI for PMID 42391447. PMID 42391447. https://doi.org/10.1002/mc.70134","words":7}],"faqs":[{"question":"What is FOXO4-DRI?","answer":"FOXO4-DRI (FOXO4) is a Research Use Only chemical-identity and literature reference on Costides, not for human or veterinary use. Published identity includes CAS 2460055-10-9, formula C228H388N86O64, average MW 5358 Da, PubChem CID 167312269. It is indexed as D-retro-inverso peptide designed to interfere with FOXO4–p53 interaction in senescence research. The CAS number of FOXO4-DRI is 2460055-10-9. Research Use Only. Not for human or veterinary use."},{"question":"What is the CAS number of FOXO4-DRI?","answer":"The CAS number of FOXO4-DRI (FOXO4) is 2460055-10-9. Formula and molecular weight appear in the identity table when retrieved."},{"question":"Is FOXO4-DRI for human use?","answer":"No. FOXO4-DRI (FOXO4) pages on Costides are Research Use Only reference materials. They are not medical advice and do not describe administration or dosing."},{"question":"What is the molecular weight of FOXO4-DRI?","answer":"The average molecular weight of FOXO4-DRI (FOXO4) listed on Costides is 5358 Da."},{"question":"Can I buy FOXO4-DRI from Costides?","answer":"Yes. FOXO4-DRI may appear in the Costides catalog as a Research Use Only 10-pack when published. Check the product listing for SKU, price, and CoA lots."},{"question":"Where does identity data for FOXO4-DRI come from?","answer":"Costides indexes registry and bibliographic sources (PubChem, CAS Common Chemistry, PubMed permalinks) when available. Outcome or efficacy claims are not restated on this page."}],"links":[{"rel":"canonical","href":"https://costides.us/us/research/foxo4-dri"},{"rel":"rag","href":"https://costides.us/api/rag/compound/foxo4-dri"},{"rel":"cas","href":"https://costides.us/us/cas/2460055-10-9"},{"rel":"llms","href":"https://costides.us/llms.txt"}]}