{"kind":"compound","id":"afamelanotide","name":"Afamelanotide","url":"https://costides.us/us/research/afamelanotide","last_verified":"2026-08-21","identity":{"cas":"75921-69-6","formula":"C78H111N21O19","mw":1646.8,"sequence":null,"sequence_3letter":null,"residues":null,"pubchem":16197727,"identity_note":null,"parent_ligand":null},"chunks":[{"id":"lead-afamelanotide","type":"definition","heading":"What is Afamelanotide?","text":"Afamelanotide (MT1) is a Research Use Only chemical-identity and literature reference on Costides, not for human or veterinary use. Published identity includes CAS 75921-69-6, formula C78H111N21O19, average MW 1646.8 Da, PubChem CID 16197727. It is indexed as alpha-MSH analogue melanocortin-1 receptor agonist.","words":42},{"id":"def-afamelanotide","type":"definition","heading":"Afamelanotide overview","text":"Afamelanotide (MT1) is a Research Use Only chemical-identity and literature reference on Costides, not for human or veterinary use. Published identity includes CAS 75921-69-6, formula C78H111N21O19, average MW 1646.8 Da, PubChem CID 16197727. It is indexed as alpha-MSH analogue melanocortin-1 receptor agonist. Synonyms and vendor codes indexed here include MT1, MT-I, Scenesse, Melanotan I, [Nle4,D-Phe7]-alpha-MSH. This page does not describe administration or dosing.","words":63},{"id":"id-afamelanotide","type":"identity","heading":"Afamelanotide chemical identity","text":"Afamelanotide chemical identity: CAS 75921-69-6; formula C78H111N21O19; average MW 1646.8 Da; PubChem CID 16197727. Values come from the Costides peptide research index.","words":22},{"id":"policy-afamelanotide","type":"policy","heading":"Research Use Only","text":"Research Use Only. Not for human or veterinary use. This page indexes chemical identity and citations. It is not medical advice and does not describe administration or dosing.","words":28},{"id":"pass-what-afamelanotide","type":"definition","heading":"What is Afamelanotide?","text":"Afamelanotide (MT1) is a Research Use Only chemical-identity and literature reference on Costides, not for human or veterinary use. Published identity includes CAS 75921-69-6, formula C78H111N21O19, average MW 1646.8 Da, PubChem CID 16197727. It is indexed as alpha-MSH analogue melanocortin-1 receptor agonist.","words":42},{"id":"pass-human-afamelanotide","type":"definition","heading":"Is Afamelanotide for human use?","text":"No. Afamelanotide (MT1) pages on Costides are Research Use Only reference materials. They are not medical advice and do not describe administration or dosing.","words":24},{"id":"pass-cas-afamelanotide","type":"definition","heading":"What is the CAS number of Afamelanotide?","text":"The CAS number of Afamelanotide (MT1) is 75921-69-6. Formula and molecular weight appear in the identity table when retrieved.","words":19},{"id":"pass-mw-afamelanotide","type":"definition","heading":"What is the molecular weight of Afamelanotide?","text":"The average molecular weight of Afamelanotide (MT1) listed on Costides is 1646.8 Da.","words":13},{"id":"faq-afamelanotide-1","type":"faq","heading":"What is Afamelanotide?","text":"Afamelanotide (MT1) is a Research Use Only chemical-identity and literature reference on Costides, not for human or veterinary use. Published identity includes CAS 75921-69-6, formula C78H111N21O19, average MW 1646.8 Da, PubChem CID 16197727. It is indexed as alpha-MSH analogue melanocortin-1 receptor agonist. The CAS number of Afamelanotide is 75921-69-6. Research Use Only. Not for human or veterinary use.","words":58},{"id":"faq-afamelanotide-2","type":"faq","heading":"What is the CAS number of Afamelanotide?","text":"The CAS number of Afamelanotide (MT1) is 75921-69-6. Formula and molecular weight appear in the identity table when retrieved.","words":19},{"id":"faq-afamelanotide-3","type":"faq","heading":"Is Afamelanotide for human use?","text":"No. Afamelanotide (MT1) pages on Costides are Research Use Only reference materials. They are not medical advice and do not describe administration or dosing.","words":24},{"id":"faq-afamelanotide-4","type":"faq","heading":"What is the molecular weight of Afamelanotide?","text":"The average molecular weight of Afamelanotide (MT1) listed on Costides is 1646.8 Da.","words":13},{"id":"faq-afamelanotide-5","type":"faq","heading":"Can I buy Afamelanotide from Costides?","text":"Yes. Afamelanotide may appear in the Costides catalog as a Research Use Only 10-pack when published. Check the product listing for SKU, price, and CoA lots.","words":26},{"id":"faq-afamelanotide-6","type":"faq","heading":"Where does identity data for Afamelanotide come from?","text":"Costides indexes registry and bibliographic sources (PubChem, CAS Common Chemistry, PubMed permalinks) when available. Outcome or efficacy claims are not restated on this page.","words":24},{"id":"cite-afamelanotide-1","type":"citation","heading":"PubChem CID 16197727","text":"PubChem CID 16197727. https://pubchem.ncbi.nlm.nih.gov/compound/16197727","words":4},{"id":"cite-afamelanotide-2","type":"citation","heading":"CAS Common Chemistry 75921-69-6","text":"CAS Common Chemistry 75921-69-6. https://commonchemistry.cas.org/detail?cas_rn=75921-69-6","words":5},{"id":"cite-afamelanotide-3","type":"citation","heading":"Heterochiral co-assembly of β-strands and hairpins affords stereocomplexed peptide hydrogels for drug delivery.","text":"Heterochiral co-assembly of β-strands and hairpins affords stereocomplexed peptide hydrogels for drug delivery.. PMID 41999898. https://pubmed.ncbi.nlm.nih.gov/41999898/","words":16},{"id":"cite-afamelanotide-4","type":"citation","heading":"DOI for PMID 41999898","text":"DOI for PMID 41999898. PMID 41999898. https://doi.org/10.1016/j.jconrel.2026.114932","words":7},{"id":"cite-afamelanotide-5","type":"citation","heading":"New and currently investigated pharmacotherapies for the erythropoietic protoporphyrias: spotlight on dersimelagon and bitopertin.","text":"New and currently investigated pharmacotherapies for the erythropoietic protoporphyrias: spotlight on dersimelagon and bitopertin.. PMID 41885813. https://pubmed.ncbi.nlm.nih.gov/41885813/","words":17},{"id":"cite-afamelanotide-6","type":"citation","heading":"DOI for PMID 41885813","text":"DOI for PMID 41885813. PMID 41885813. https://doi.org/10.1080/14656566.2026.2651281","words":7}],"faqs":[{"question":"What is Afamelanotide?","answer":"Afamelanotide (MT1) is a Research Use Only chemical-identity and literature reference on Costides, not for human or veterinary use. Published identity includes CAS 75921-69-6, formula C78H111N21O19, average MW 1646.8 Da, PubChem CID 16197727. It is indexed as alpha-MSH analogue melanocortin-1 receptor agonist. The CAS number of Afamelanotide is 75921-69-6. Research Use Only. Not for human or veterinary use."},{"question":"What is the CAS number of Afamelanotide?","answer":"The CAS number of Afamelanotide (MT1) is 75921-69-6. Formula and molecular weight appear in the identity table when retrieved."},{"question":"Is Afamelanotide for human use?","answer":"No. Afamelanotide (MT1) pages on Costides are Research Use Only reference materials. They are not medical advice and do not describe administration or dosing."},{"question":"What is the molecular weight of Afamelanotide?","answer":"The average molecular weight of Afamelanotide (MT1) listed on Costides is 1646.8 Da."},{"question":"Can I buy Afamelanotide from Costides?","answer":"Yes. Afamelanotide may appear in the Costides catalog as a Research Use Only 10-pack when published. Check the product listing for SKU, price, and CoA lots."},{"question":"Where does identity data for Afamelanotide come from?","answer":"Costides indexes registry and bibliographic sources (PubChem, CAS Common Chemistry, PubMed permalinks) when available. Outcome or efficacy claims are not restated on this page."}],"links":[{"rel":"canonical","href":"https://costides.us/us/research/afamelanotide"},{"rel":"rag","href":"https://costides.us/api/rag/compound/afamelanotide"},{"rel":"cas","href":"https://costides.us/us/cas/75921-69-6"},{"rel":"llms","href":"https://costides.us/llms.txt"}]}